Akip1^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Akip1^em1Cya
• Name: A kinase interacting protein 1; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7327293
• Gene: Akip1 Location: Chr7:109302897-109311396 bp, + strand Genetic Position: Chr7, 57.44 cM
• Alliance: Akip1^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology targeting exon 4 generated a 28-bp deletion. (J:326919)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Akip1 Mutation: 22 strains or lines available

References

• Original: J:326919 Zhu L, et al., Ebola virus VP35 hijacks the PKA-CREB1 pathway for replication and pathogenesis by AKIP1 association. Nat Commun. 2022 Apr 26;13(1):2256
• All: 1 reference(s)