Slitrk2^tm1.1Jaru
Targeted Allele Detail

Summary

• Symbol: Slitrk2^tm1.1Jaru
• Name: SLIT and NTRK-like family, member 2; targeted mutation 1.1, Jun Aruga
• MGI ID: MGI:7327302
• Gene: Slitrk2 Location: ChrX:65692924-65704999 bp, + strand Genetic Position: ChrX, 34.81 cM, cytoband A5
• Alliance: Slitrk2^tm1.1Jaru page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326787
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector replaced the entire open-reading frame with a floxed neo. Cre-mediated recombination removed the selection cassette. (J:326787)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slitrk2 Mutation: 6 strains or lines available

References

• Original: J:326787 Katayama KI, et al., Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation. iScience. 2022 Jul 15;25(7):104604
• All: 1 reference(s)