Trim6^em1Raj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim6^em1Raj
• Name: tripartite motif-containing 6; endonuclease-mediated mutation 1, Ricardo Rajsbaum
• MGI ID: MGI:7327325
• Gene: Trim6 Location: Chr7:103868002-103884359 bp, + strand Genetic Position: Chr7, 55.55 cM, cytoband F1
• Alliance: Trim6^em1Raj page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated an 8 bp deletion (TGTGCCGG) in exon 2. (J:326927)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim6 Mutation: 55 strains or lines available

References

• Original: J:326927 van Tol S, et al., Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly. PLoS Pathog. 2022 May;18(5):e1010532
• All: 1 reference(s)