Mast4^em1Sjkm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mast4^em1Sjkm
• Name: microtubule associated serine/threonine kinase family member 4; endonuclease-mediated mutation 1, Seong-Jin Kim
• MGI ID: MGI:7327411
• Gene: Mast4 Location: Chr13:102868994-103471005 bp, - strand Genetic Position: Chr13, 54.94 cM
• Alliance: Mast4^em1Sjkm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting introduced deletions mutations in exon 1 (71 bp deletion) and 15 (3 bp deletion). (J:326767)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mast4 Mutation: 118 strains or lines available

References

• Original: J:326767 Kim P, et al., Mast4 determines the cell fate of MSCs for bone and cartilage development. Nat Commun. 2022 Jul 8;13(1):3960
• All: 4 reference(s)