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Aldh1a2tm1.1Mbp
Targeted Allele Detail
Summary
Symbol: Aldh1a2tm1.1Mbp
Name: aldehyde dehydrogenase family 1, subfamily A2; targeted mutation 1.1, Mouse Biology Program, UC Davis
MGI ID: MGI:7327620
Synonyms: Aldh1a2fl
Gene: Aldh1a2  Location: Chr9:71123071-71203525 bp, + strand  Genetic Position: Chr9, 39.85 cM
Alliance: Aldh1a2tm1.1Mbp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:324714
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe targeting vector inserted into intron 3 an FRT-flanked neomycin resistance cassette with a 3' UTR and into intron 4 an additional loxP site. Flp-mediated recombination removed the selection cassette and left exon 4 floxed. (J:324714)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aldh1a2 Mutation:  38 strains or lines available
References
Original:  J:324714 Beedle MT, et al., Sources of all-trans retinal oxidation independent of the aldehyde dehydrogenase 1A isozymes exist in the postnatal testis. Biol Reprod. 2019 Feb 1;100(2):547-560
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory