Enkd1^em1Jzho
Endonuclease-mediated Allele Detail

Summary

• Symbol: Enkd1^em1Jzho
• Name: enkurin domain containing 1; endonuclease-mediated mutation 1, Jun Zhou
• MGI ID: MGI:7328569
• Gene: Enkd1 Location: Chr8:106430283-106434842 bp, - strand Genetic Position: Chr8, 53.04 cM
• Alliance: Enkd1^em1Jzho page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology deleted exon 3 and adjacent flanking sequences. Western blot analysis confirmed absence of protein. (J:326906)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Enkd1 Mutation: 12 strains or lines available

References

• Original: J:326906 Song T, et al., ENKD1 promotes CP110 removal through competing with CEP97 to initiate ciliogenesis. EMBO Rep. 2022 May 4;23(5):e54090
• All: 1 reference(s)