Kif2c^em1Nju
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kif2c^em1Nju
• Name: kinesin family member 2C; endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:7328589
• Gene: Kif2c Location: Chr4:117016830-117039821 bp, - strand Genetic Position: Chr4, 53.42 cM, cytoband D1
• Alliance: Kif2c^em1Nju page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exons 3 through 8. (J:322820)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif2c Mutation: 34 strains or lines available

References

• Original: J:322820 Zheng R, et al., KIF2C regulates synaptic plasticity and cognition in mice through dynamic microtubule depolymerization. Elife. 2022 Feb 9;11:e72483
• All: 1 reference(s)