Tg(ADRB1-cre)#Ljp
Transgene Detail

Summary

• Symbol: Tg(ADRB1-cre)#Ljp
• Name: transgene insertion, Louis Ptacek
• MGI ID: MGI:7328730
• Synonyms: ADRB1-Cre
• Transgene: Tg(ADRB1-cre)#Ljp Location: unknown
• Alliance: Tg(ADRB1-cre)#Ljp page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(ADRB1-cre)#Ljp expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  ADRB1 (153)

  Adrb1

  (MGI:87937)

• Mutation details: The coding sequence of ADRB1 in the human BAC: CTD2337B3, containing the entire ADRB1 gene on a 150-kb insert was replaced by that of Cre. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:282569)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	ADRB1 (human) Summary of all recombinase alleles driven by ADRB1. Comparative matrix view of recombinase activities Alliance human ADRB1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:282569 Shi G, et al., A Rare Mutation of beta1-Adrenergic Receptor Affects Sleep/Wake Behaviors. Neuron. 2019 Sep 25;103(6):1044-1055.e7
• All: 2 reference(s)