Kcnt1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Kcnt1^tm1Dgen
• Name: potassium channel, subfamily T, member 1; targeted mutation 1, Deltagen
• MGI ID: MGI:7328749
• Gene: Kcnt1 Location: Chr2:25753807-25808285 bp, + strand Genetic Position: Chr2, 18.27 cM
• Alliance: Kcnt1^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:322801
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced exons 7 through 11 with an IRES lacZ/neo reporter and selection cassette. (J:322801)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnt1 Mutation: 67 strains or lines available

References

• Original: J:322801 Liu Y, et al., The Slack Channel Deletion Causes Mechanical Pain Hypersensitivity in Mice. Front Mol Neurosci. 2022;15:811441
• All: 2 reference(s)