Dock10^tm1Thar
Targeted Allele Detail

Summary

• Symbol: Dock10^tm1Thar
• Name: dedicator of cytokinesis 10; targeted mutation 1, Takayuki Harada
• MGI ID: MGI:7330190
• Gene: Dock10 Location: Chr1:80478790-80736244 bp, - strand Genetic Position: Chr1, 41.41 cM
• Alliance: Dock10^tm1Thar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:300632
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance gene replaced most of exon 5, exon 6, and most of exon 7. (J:300632)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dock10 Mutation: 140 strains or lines available

References

• Original: J:300632 Namekata K, et al., Roles of the DOCK-D family proteins in a mouse model of neuroinflammation. J Biol Chem. 2020 May 8;295(19):6710-6720
• All: 1 reference(s)