Gt(ROSA)26Sor^{em#(CAG-Fstl5)Jrio}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{em#(CAG-Fstl5)Jrio}
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation, Jonathan J Rios
• MGI ID: MGI:7331585
• Synonyms: Fstl5^LSL
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{em#(CAG-Fstl5)Jrio} page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{em#(CAG-Fstl5)Jrio} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fstl5 (MGI:2442179)

• Mutation details: A CAG promoter, loxP-flanked STOP cassette, and mouse Fstl5 were inserted into the locus. Multiple lines were established and the pound symbol (#) is used when line is not specified and/or lines are pooled. (J:301587)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:301587 Khanshour AM, et al., Genetic association and characterization of FSTL5 in isolated clubfoot. Hum Mol Genet. 2021 Jan 21;29(22):3717-3728
• All: 1 reference(s)