Tg(KRT14-Shh)#Cobm
Transgene Detail

Summary

• Symbol: Tg(KRT14-Shh)#Cobm
• Name: transgene insertion, Martyn T Cobourne
• MGI ID: MGI:7332932
• Synonyms: K14-Shh
• Transgene: Tg(KRT14-Shh)#Cobm Location: unknown
• Alliance: Tg(KRT14-Shh)#Cobm page

Transgene origin

• Strain of Origin: CBA x C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-Shh)#Cobm expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Shh (MGI:98297)

• The human KRT14 promoter drives expression of a full length mouse Shh open reading frame. (J:150375)

Disease models

Expression

In Structures Affected by this Mutation:

23 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:150375 Cobourne MT, et al., Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome. Dev Biol. 2009 Jul 1;331(1):38-49
• All: 2 reference(s)