Cd200l2^tm1.1Hkar
Targeted Allele Detail

Summary

• Symbol: Cd200l2^tm1.1Hkar
• Name: CD200 molecule like 2; targeted mutation 1.1, Hajime Karasuyama
• MGI ID: MGI:7334726
• Gene: Cd200l2 Location: Chr16:45332154-45352413 bp, - strand Genetic Position: Chr16, 29.53 cM
• Alliance: Cd200l2^tm1.1Hkar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326965
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The targeting construct replaced exon 2, intron 2, and exon 3 with a floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. (J:326965)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd200l2 Mutation: 5 strains or lines available

References

• Original: J:326965 van der Vlist M, et al., Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain. Neuron. 2022 Feb 16;110(4):613-626.e9
• All: 1 reference(s)