Lgr4^em1Asc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lgr4^em1Asc
• Name: leucine-rich repeat-containing G protein-coupled receptor 4; endonuclease-mediated mutation 1, Andreas Schedl
• MGI ID: MGI:7336812
• Gene: Lgr4 Location: Chr2:109747992-109844602 bp, + strand Genetic Position: Chr2, 56.65 cM
• Alliance: Lgr4^em1Asc page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 3 deleted 5 bp. (J:264603)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:

14 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lgr4 Mutation: 94 strains or lines available

References

• Original: J:264603 Da Silva F, et al., Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4. Dev Biol. 2018 Sep 1;441(1):42-51
• All: 1 reference(s)