Krt7^{tm1(cre/ERT2)Que}
Targeted Allele Detail

Summary

• Symbol: Krt7^{tm1(cre/ERT2)Que}
• Name: keratin 7; targeted mutation 1, Jianwen Que
• MGI ID: MGI:7336814
• Synonyms: Krt7^CreER
• Gene: Krt7 Location: Chr15:101310284-101325687 bp, + strand Genetic Position: Chr15, 56.88 cM
• Alliance: Krt7^{tm1(cre/ERT2)Que} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:252735
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Null/knockout, Recombinase)
• Inducer: tamoxifen
• Mutations: Insertion, Intragenic deletion
• Krt7^{tm1(cre/ERT2)Que} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Krt7 (MGI:96704)

• The allele was generated by replacing the CreER cassette at the ATG of the Krt7 gene. (J:252735)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Krt7 (mouse) Summary of all recombinase alleles driven by Krt7. Comparative matrix view of recombinase activities Alliance mouse Krt7 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Krt7 Mutation: 30 strains or lines available

References

• Original: J:252735 Jiang M, et al., Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus. Nature. 2017 Oct 26;550(7677):529-533
• All: 2 reference(s)