Ftsj1^tm1Tomik
Targeted Allele Detail

Summary

• Symbol: Ftsj1^tm1Tomik
• Name: FtsJ RNA 2'-O-methyltransferase 1; targeted mutation 1, Kazuhito Tomizawa
• MGI ID: MGI:7341380
• Gene: Ftsj1 Location: ChrX:8104907-8118609 bp, - strand Genetic Position: ChrX, 3.73 cM
• Alliance: Ftsj1^tm1Tomik page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:328916
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 2 to 5 were replaced with a neomycin resistance gene. (J:328916)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ftsj1 Mutation: 34 strains or lines available

References

• Original: J:328916 Nagayoshi Y, et al., Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability. Sci Adv. 2021 Mar;7(13)
• All: 1 reference(s)