Ihh^{em1(Tomm20/mKate2,dre)Xya}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ihh^{em1(Tomm20/mKate2,dre)Xya}
• Name: Indian hedgehog; endonuclease-mediated mutation 1, Xiao Yang
• MGI ID: MGI:7341589
• Synonyms: Ihh-mKate2^tomm20-Dre
• Gene: Ihh Location: Chr1:74984474-74990831 bp, - strand Genetic Position: Chr1, 38.55 cM
• Alliance: Ihh^{em1(Tomm20/mKate2,dre)Xya} page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase, Reporter)
• Mutation: Insertion
• Ihh^{em1(Tomm20/mKate2,dre)Xya} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ihh (MGI:96533)

• CRISPR/Cas9-system was used to introduce a P2A-Tomm20/mKate2-P2A-Dre just behind the last exon. (J:327630)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ihh (mouse) Summary of all recombinase alleles driven by Ihh. Comparative matrix view of recombinase activities Alliance mouse Ihh gene page

Expression

In Mice Carrying this Mutation:

42 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ihh Mutation: 22 strains or lines available

References

• Original: J:327630 Li R, et al., Generation of an Ihh-mKate2-Dre knock-in mouse line. Genesis. 2022 Jul;60(6-7):e23488
• All: 1 reference(s)