Tg(Sox2-cre/ERT2)194.34Ics
Transgene Detail

Summary

• Symbol: Tg(Sox2-cre/ERT2)194.34Ics
• Name: transgene insertion 194.34, Mouse Clinical Institute
• MGI ID: MGI:7346252
• Transgene: Tg(Sox2-cre/ERT2)194.34Ics Location: unknown
• Alliance: Tg(Sox2-cre/ERT2)194.34Ics page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Sox2-cre/ERT2)194.34Ics expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Sox2 (MGI:98364)

• Mutation details: The line was obtained by microinjection of a circular murine BAC transgene (RP23-423J10) previously modified by recombineering at the ATG of the Sox2 gene of a rabbit-beta-globin intron-cre/ERT2 cassette followed by a flipped PGK-Tn5-Kana/NeoR cassette. The subline 194.34 was analyzed and cryopreserved. (J:234752)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sox2 (mouse) Summary of all recombinase alleles driven by Sox2. Alliance mouse Sox2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:234752 Liu S, et al., Skin progenitor cells contribute to bleomycin-induced skin fibrosis. Arthritis Rheumatol. 2014 Mar;66(3):707-13
• All: 1 reference(s)