Serpinb9b^em#Tvg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Serpinb9b^em#Tvg
• Name: serine (or cysteine) peptidase inhibitor, clade B, member 9b; endonuclease-mediated mutation, Tatyana Golovkina
• MGI ID: MGI:7354909
• Gene: Serpinb9b Location: Chr13:33211397-33224571 bp, + strand Genetic Position: Chr13, 13.79 cM
• Alliance: Serpinb9b^em#Tvg page

Mutation origin

• Strain of Origin: BALB/cJ

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology targeted exon 2. Two lines were produced with one having a 197bp deletion and the other a 512bp deletion. This record represents pooled data from the two lines. (J:329456)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Serpinb9b Mutation: 33 strains or lines available

References

• Original: J:329456 Spring J, et al., Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus. Cell Rep. 2022 Sep 13;40(11):111341
• All: 1 reference(s)