Vsig4^em#Tvg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Vsig4^em#Tvg
• Name: V-set and immunoglobulin domain containing 4; endonuclease-mediated mutation, Tatyana Golovkina
• MGI ID: MGI:7354911
• Synonyms: VSig4^-
• Gene: Vsig4 Location: ChrX:95290809-95337044 bp, - strand Genetic Position: ChrX, 42.69 cM
• Alliance: Vsig4^em#Tvg page

Mutation origin

• Strain of Origin: BALB/cJ

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology targeted exon 1. Five lines were produced with deletions ranging from 32bp to 57bp. This record represents pooled data from the five lines. (J:329456)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vsig4 Mutation: 10 strains or lines available

References

• Original: J:329456 Spring J, et al., Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus. Cell Rep. 2022 Sep 13;40(11):111341
• All: 1 reference(s)