Trim11^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim11^em1Bcgen
• Name: tripartite motif-containing 11; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7354926
• Gene: Trim11 Location: Chr11:58868919-58882284 bp, + strand Genetic Position: Chr11, 36.4 cM, cytoband B2
• Alliance: Trim11^em1Bcgen page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 2 to 6. (J:329445)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim11 Mutation: 22 strains or lines available

References

• Original: J:329445 Xiao Q, et al., Regulation of KDM5C stability and enhancer reprogramming in breast cancer. Cell Death Dis. 2022 Oct 3;13(10):843
• All: 1 reference(s)