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Zfp28em1(IMPC)J
Endonuclease-mediated Allele Detail
Summary
Symbol: Zfp28em1(IMPC)J
Name: zinc finger protein 28; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:7356590
Gene: Zfp28  Location: Chr7:6386317-6399636 bp, + strand  Genetic Position: Chr7, 3.7 cM
Alliance: Zfp28em1(IMPC)J page
IMPC: Zfp28 gene page
Mutation
origin
Strain of Origin:  C57BL/6NJ
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CACGATCACAGGTCACCAGA and GTAAGACTGACAGGGAAAGG, which resulted in a 602 bp deletion beginning at Chromosome 7 position 6,389,393 bp and ending after 6,389,994 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000992229 and ENSMUSE00000464573 (exons 3 and 4) and 379 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 100 and early truncation 1 amino acid later. (J:188991)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Zfp28 Mutation:  42 strains or lines available
References
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory