Rbm46^em3Rpc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rbm46^em3Rpc
• Name: RNA binding motif protein 46; endonuclease-mediated mutation 3, Russ P Carstens
• MGI ID: MGI:7356604
• Synonyms: Rbm46^fl
• Gene: Rbm46 Location: Chr3:82744535-82783790 bp, - strand Genetic Position: Chr3, 36.75 cM
• Alliance: Rbm46^em3Rpc page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 technology inserted loxP sites flanking exons 3 and 4, which contain all three RNA Recognition Motifs (RRMs). (J:330079)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbm46 Mutation: 25 strains or lines available

References

• Original: J:330079 Peart NJ, et al., The germ cell-specific RNA binding protein RBM46 is essential for spermatogonial differentiation in mice. PLoS Genet. 2022 Sep;18(9):e1010416
• All: 1 reference(s)