Xpo4^em1Gshan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Xpo4^em1Gshan
• Name: exportin 4; endonuclease-mediated mutation 1, Ge Shan
• MGI ID: MGI:7356624
• Synonyms: XPO4^-
• Gene: Xpo4 Location: Chr14:57814978-57902887 bp, - strand Genetic Position: Chr14, 30.11 cM, cytoband C2
• Alliance: Xpo4^em1Gshan page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated an approximate 10 kb deletion encompassing exons 4-6. (J:330082)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Xpo4 Mutation: 85 strains or lines available

References

• Original: J:330082 Chen L, et al., Exportin 4 depletion leads to nuclear accumulation of a subset of circular RNAs. Nat Commun. 2022 Oct 1;13(1):5769
• All: 1 reference(s)