Aldh3b2^em1Akih
Endonuclease-mediated Allele Detail

Summary

• Symbol: Aldh3b2^em1Akih
• Name: aldehyde dehydrogenase 3 family, member B2; endonuclease-mediated mutation 1, Akio Kihara
• MGI ID: MGI:7367353
• Gene: Aldh3b2 Location: Chr19:4022328-4031646 bp, + strand Genetic Position: Chr19, 3.69 cM
• Alliance: Aldh3b2^em1Akih page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 deleted 1 bp and 7 bp. (J:330263)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Aldh3b2 Mutation: 23 strains or lines available

References

• Original: J:330263 Nojiri K, et al., Impaired Skin Barrier Function Due to Reduced omega-O-Acylceramide Levels in a Mouse Model of Sjogren-Larsson Syndrome. Mol Cell Biol. 2021;41(10):e0035221
• All: 1 reference(s)