Awat1^em1Akih
Endonuclease-mediated Allele Detail

Summary

• Symbol: Awat1^em1Akih
• Name: acyl-CoA wax alcohol acyltransferase 1; endonuclease-mediated mutation 1, Akio Kihara
• MGI ID: MGI:7367579
• Gene: Awat1 Location: ChrX:99615857-99621811 bp, + strand Genetic Position: ChrX, 43.72 cM
• Alliance: Awat1^em1Akih page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 3 inserted 11 bp. (J:330312)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Awat1 Mutation: 5 strains or lines available

References

• Original: J:330312 Sawai M, et al., Diverse meibum lipids produced by Awat1 and Awat2 are important for stabilizing tear film and protecting the ocular surface. iScience. 2021;24(5):102478
• All: 1 reference(s)