Rtl6^tm1.1Tmki
Targeted Allele Detail

Summary

• Symbol: Rtl6^tm1.1Tmki
• Name: retrotransposon Gag like 6; targeted mutation 1.1, Tomoko Kaneko-Ishino
• MGI ID: MGI:7378508
• Synonyms: Rtl6-Venus
• Gene: Rtl6 Location: Chr15:84437599-84442024 bp, - strand Genetic Position: Chr15, 39.88 cM
• Alliance: Rtl6^tm1.1Tmki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:329352
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a Venus reporter gene downstream of the coding region followed by an FRT and loxP site. Cre-mediated recombination removed the floxed region. (J:329352)

Expression

In Mice Carrying this Mutation:

49 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rtl6 Mutation: 10 strains or lines available

References

• Original: J:329352 Irie M, et al., Retrovirus-derived RTL5 and RTL6 genes are novel constituents of the innate immune system in the eutherian brain. Development. 2022 Sep 15;149(18):dev200976
• All: 1 reference(s)