Rtl5^tm1.1Tmki
Targeted Allele Detail

Summary

• Symbol: Rtl5^tm1.1Tmki
• Name: retrotransposon Gag like 5; targeted mutation 1.1, Tomoko Kaneko-Ishino
• MGI ID: MGI:7378511
• Gene: Rtl5 Location: ChrX:101110150-101114910 bp, - strand Genetic Position: ChrX, 45.06 cM
• Alliance: Rtl5^tm1.1Tmki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:329352
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct deleted the coding sequence leaving behind a single FRT and loxP site following recombinase removal of the FRT flanked neomycin resistance cassette. (J:329352)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rtl5 Mutation: 6 strains or lines available

References

• Original: J:329352 Irie M, et al., Retrovirus-derived RTL5 and RTL6 genes are novel constituents of the innate immune system in the eutherian brain. Development. 2022 Sep 15;149(18):dev200976
• All: 2 reference(s)