Rnf133^em1Zuk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf133^em1Zuk
• Name: ring finger protein 133; endonuclease-mediated mutation 1, Martin M Matzuk
• MGI ID: MGI:7378666
• Gene: Rnf133 Location: Chr6:23648868-23650304 bp, - strand Genetic Position: Chr6, 11.01 cM
• Alliance: Rnf133^em1Zuk page

Mutation origin

• Strain of Origin: (C57BL/6NCrl x DBA/2NCrl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 1070 bp deletion in exon 1 (J:330415)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf133 Mutation: 12 strains or lines available

References

• Original: J:330415 Nozawa K, et al., The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice. BMC Biol. 2022 Jul 13;20(1):161
• All: 1 reference(s)