Zswim2^em1Zuk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zswim2^em1Zuk
• Name: zinc finger SWIM-type containing 2; endonuclease-mediated mutation 1, Martin M Matzuk
• MGI ID: MGI:7378669
• Gene: Zswim2 Location: Chr2:83745423-83771572 bp, - strand Genetic Position: Chr2, 49.33 cM, cytoband E1
• Alliance: Zswim2^em1Zuk page

Mutation origin

• Strain of Origin: (C57BL/6NCrl x DBA/2NCrl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 25842 bp deletion encompassing most of the coding sequence. (J:330415)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zswim2 Mutation: 36 strains or lines available

References

• Original: J:330415 Nozawa K, et al., The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice. BMC Biol. 2022 Jul 13;20(1):161
• All: 1 reference(s)