Cdh8^{tm2c(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Cdh8^{tm2c(KOMP)Wtsi}
• Name: cadherin 8; targeted mutation 2c, Wellcome Trust Sanger Institute
• MGI ID: MGI:7378842
• Synonyms: Cdh8^FL
• Gene: Cdh8 Location: Chr8:99751103-100143103 bp, - strand Genetic Position: Chr8, 49.4 cM
• Alliance: Cdh8^{tm2c(KOMP)Wtsi} page

Mutation origin

• Mutant Cell Line: EPD0514_2_F07
• Germline Transmission: Earliest citation of germline transmission: J:341683
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: The cassette is composed of an FRT site, a beta galactosidase sequence, a loxP site, a neomycin resistance (neo) cassette, second FRT site and a second loxP site and is inserted upstream of exon 3. A third loxP site is inserted downstream of exon 3. Flp-mediated recombination removed the lacZ and neo cassette.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cdh8 Mutation: 53 strains or lines available

References

• Original: J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009
• All: 2 reference(s)