Tg(Nppa-lacZ)m-0.7Vmc
Transgene Detail

Summary

• Symbol: Tg(Nppa-lacZ)m-0.7Vmc
• Name: transgene insertion m-0.7, Vincent M Christoffels
• MGI ID: MGI:7382811
• Synonyms: -0.7mLacZ
• Transgene: Tg(Nppa-lacZ)m-0.7Vmc Location: unknown
• Alliance: Tg(Nppa-lacZ)m-0.7Vmc page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The 638/+70 bp mouse Nppa regulatory region sequence, containing the promoter and silencer and enhancer sequences, is placed upstream of a beta-globin/IgG chimeric intron, nls sequence, the lacZ beta-galactosidase gene and bovine GH poly(A) signal sequence. The regulatory sequence drives expression in the embryonic atrial and ventricular chamber myocardium. (J:278530)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:278530 Horsthuis T, et al., Distinct regulation of developmental and heart disease-induced atrial natriuretic factor expression by two separate distal sequences. Circ Res. 2008 Apr 11;102(7):849-59
• All: 1 reference(s)