Nps^{em1(cre)Jgeer}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nps^{em1(cre)Jgeer}
• Name: neuropeptide S; endonuclease-mediated mutation 1, Joel C Geerling
• MGI ID: MGI:7382970
• Synonyms: Nps-2A-Cre
• Gene: Nps Location: Chr7:134870348-134874671 bp, + strand Genetic Position: Chr7, 81.27 cM
• Alliance: Nps^{em1(cre)Jgeer} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Nps^{em1(cre)Jgeer} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nps (MGI:3642232)

• Using CRISPR-Cas9 technology, 2A-Cre was inserted downstream of the endogenous Nps gene. (J:330690)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nps (mouse) Summary of all recombinase alleles driven by Nps. Comparative matrix view of recombinase activities Alliance mouse Nps gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nps Mutation: 15 strains or lines available

References

• Original: J:330690 Huang D, et al., Neuropeptide S (NPS) neurons: Parabrachial identity and novel distributions. J Comp Neurol. 2022;530(18):3157-3178
• All: 1 reference(s)