Rr282729^tm1.1Iku
Targeted Allele Detail

Summary

• Symbol: Rr282729^tm1.1Iku
• Name: regulatory region 282729; targeted mutation 1.1, Koichi Ikuta
• MGI ID: MGI:7383032
• Synonyms: Egamma4^-
• Gene: Rr282729 Location: Chr13:19540202-19541400 bp, . strand Genetic Position: Chr13, Syntenic
• Alliance: Rr282729^tm1.1Iku page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:288442
• Parent Cell Line: KY1.1 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion
• Mutation details: A 1006-bp genomic sequence containing the Tcrg enhancer was replaced with a loxP site flanked neomycin resistance gene cassette, which was removed through subsequent cre-mediated recombination. (J:288442)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr282729 Mutation: 0 strains or lines available

References

• Original: J:288442 Tani-Ichi S, et al., Innate-like CD27(+)CD45RB(high) gammadelta T Cells Require TCR Signaling for Homeostasis in Peripheral Lymphoid Organs. J Immunol. 2020 May 15;204(10):2671-2684
• All: 1 reference(s)