Ankrd60^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ankrd60^em1(IMPC)J
• Name: ankyrin repeat domain 60; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7384345
• Gene: Ankrd60 Location: Chr2:173410451-173420066 bp, - strand Genetic Position: Chr2, 97.04 cM, cytoband H3
• Alliance: Ankrd60^em1(IMPC)J page
• IMPC: Ankrd60 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTGTTGATAAGCAAGCCCGA and GCGTGATTCAGGGCCAGACG, which resulted in a 360 bp deletion beginning at Chromosome 2 position 173,572,334 bp and ending after 173,572,693 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001273680 (exon 2) and 229 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 117 and early truncation 20 amino acids later. (J:188991)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ankrd60 Mutation: 20 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 2 reference(s)