Ark2n^em1Wehi
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ark2n^em1Wehi
• Name: arkadia (RNF111) N-terminal like PKA signaling regulator 2N; endonuclease-mediated mutation 1, Walter and Eliza Hall Institute of Medical Research
• MGI ID: MGI:7384485
• Gene: Ark2n Location: Chr18:77719193-77802186 bp, - strand Genetic Position: Chr18, 52.38 cM
• Alliance: Ark2n^em1Wehi page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology excised the entire gene (43,389 bp). (J:330717)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ark2n Mutation: 79 strains or lines available

References

• Original: J:330717 Blazev R, et al., Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function. Cell Metab. 2022 Jul 19
• All: 1 reference(s)