Tubb3^{tm1.1(cre)Ksak}
Targeted Allele Detail

Summary

• Symbol: Tubb3^{tm1.1(cre)Ksak}
• Name: tubulin, beta 3 class III; targeted mutation 1.1, Kenji Sakimura
• MGI ID: MGI:7384619
• Synonyms: Tubb3-cre
• Gene: Tubb3 Location: Chr8:124138292-124148754 bp, + strand Genetic Position: Chr8, 72.1 cM
• Alliance: Tubb3^{tm1.1(cre)Ksak} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:327011
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Recombinase, Reporter)
• Mutation: Insertion
• Tubb3^{tm1.1(cre)Ksak} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tubb3 (MGI:107813)

• Cre/IRES/EGFP knockin mice targeted at the Tubb3 gene locus. (J:327011)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tubb3 (mouse) Summary of all recombinase alleles driven by Tubb3. Alliance mouse Tubb3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tubb3 Mutation: 32 strains or lines available

References

• Original: J:327011 Abe Y, et al., Optical manipulation of local cerebral blood flow in the deep brain of freely moving mice. Cell Rep. 2021 Jul 27;36(4):109427
• All: 1 reference(s)