Rps9^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Rps9^tm1.1Geno
• Name: ribosomal protein S9; targeted mutation 1.1, Genoway
• MGI ID: MGI:7384901
• Synonyms: Rps9^D95N
• Gene: Rps9 Location: Chr7:3707035-3709896 bp, + strand Genetic Position: Chr7, 2.13 cM, cytoband A1
• Alliance: Rps9^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:329922
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: The targeting construct inserted the mutation responsible for the amino acid substitution of aspartic acid with asparagine at position 95 (D95N). Cre-mediated recombination removed the floxed neomycin resistance cassette inserted in intron 3. (J:329922)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rps9 Mutation: 16 strains or lines available

References

• Original: J:329922 Shcherbakov D, et al., Premature aging in mice with error-prone protein synthesis. Sci Adv. 2022 Mar 4;8(9):eabl9051
• All: 2 reference(s)