Gm16364^tm1Zhaoy
Targeted Allele Detail

Summary

• Symbol: Gm16364^tm1Zhaoy
• Name: predicted gene 16364; targeted mutation 1, Yun Zhao
• MGI ID: MGI:7386870
• Synonyms: Hilnc^BM
• Gene: Gm16364 Location: Chr10:39432067-39489678 bp, - strand Genetic Position: Chr10, 20.78 cM
• Alliance: Gm16364^tm1Zhaoy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:322340
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Nucleotide substitutions
• The targeting construct mutated the Gli-binding site in the promoter region. (J:322340)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gm16364 Mutation: 1 strain or line available

References

• Original: J:322340 Jiang Y, et al., Loss of Hilnc prevents diet-induced hepatic steatosis through binding of IGF2BP2. Nat Metab. 2021 Nov;3(11):1569-1584
• All: 1 reference(s)