Jmjd8^em1Kaso
Endonuclease-mediated Allele Detail

Summary

• Symbol: Jmjd8^em1Kaso
• Name: jumonji domain containing 8; endonuclease-mediated mutation 1, Sona Kang
• MGI ID: MGI:7386879
• Gene: Jmjd8 Location: Chr17:26048017-26050817 bp, + strand Genetic Position: Chr17, 12.92 cM, cytoband B1
• Alliance: Jmjd8^em1Kaso page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 240 bp deletion that includes the start codon. (J:319518)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Jmjd8 Mutation: 19 strains or lines available

References

• Original: J:319518 You D, et al., JMJD8 is a Novel Molecular Nexus Between Adipocyte-Intrinsic Inflammation and Insulin Resistance. Diabetes. 2021 Oct 21
• All: 1 reference(s)