Rn7sk^tm1.2Mfrye
Targeted Allele Detail

Summary

• Symbol: Rn7sk^tm1.2Mfrye
• Name: RNA, 7SK, nuclear; targeted mutation 1.2, Michaela Frye
• MGI ID: MGI:7386923
• Gene: Rn7sk Location: Chr9:78082585-78082915 bp, - strand Genetic Position: Chr9, 43.63 cM
• Alliance: Rn7sk^tm1.2Mfrye page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:331226
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct floxed the coding region and TATA sequence. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed the floxed segment. (J:331226)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rn7sk Mutation: 2 strains or lines available

References

• Original: J:331226 Bandiera R, et al., RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin. Nat Commun. 2021 Oct 7;12(1):5864
• All: 1 reference(s)