Crot^em1Akw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Crot^em1Akw
• Name: carnitine O-octanoyltransferase; endonuclease-mediated mutation 1, Elena Aikawa
• MGI ID: MGI:7386925
• Gene: Crot Location: Chr5:9016033-9047324 bp, - strand Genetic Position: Chr5, 3.5 cM, cytoband A1
• Alliance: Crot^em1Akw page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed exon 3. (J:331161)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crot Mutation: 46 strains or lines available

References

• Original: J:331161 Okui T, et al., CROT (Carnitine O-Octanoyltransferase) Is a Novel Contributing Factor in Vascular Calcification via Promoting Fatty Acid Metabolism and Mitochondrial Dysfunction. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):755-768
• All: 1 reference(s)