Zfp385c^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zfp385c^em1(IMPC)J
• Name: zinc finger protein 385C; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7388258
• Gene: Zfp385c Location: Chr11:100518369-100583281 bp, - strand Genetic Position: Chr11, 63.47 cM
• Alliance: Zfp385c^em1(IMPC)J page
• IMPC: Zfp385c gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GATTTCAAGTTCACACAACG and GTCTCATGCCTCATCTAGGA, which resulted in a 257 bp deletion beginning at Chromosome 11 position 100,632,662 bp and ending after 100,632,918 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001256338 (exon 4) and 91 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 89 and early truncation 72 amino acids later. (J:188991)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Zfp385c Mutation: 12 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 2 reference(s)