Tg(MPSV-Tcra,Tcrb)1Kshs
Transgene Detail
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Symbol: |
Tg(MPSV-Tcra,Tcrb)1Kshs |
Name: |
transgene insertion 1, Hans Schreiber |
MGI ID: |
MGI:7397255 |
Synonyms: |
1D9Tg, Tg(Mp71-1D9) |
Transgene: |
Tg(MPSV-Tcra,Tcrb)1Kshs Location: unknown
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Alliance: |
Tg(MPSV-Tcra,Tcrb)1Kshs page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(MPSV-Tcra,Tcrb)1Kshs expresses
2 genes
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Tcra (MGI:98553) |
specific to UV-induced mouse tumor 8101 (MP71-1D9) |
mouse |
Tcrb (MGI:98578) |
specific to UV-induced mouse tumor 8101 (MP71-1D9) |
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Mutation details: The viral vector expresses a high avidity T cell receptor (TCR) specific to UV-induced mouse tumor 8101 (MP71-1D9) driven by the mouse myeloproliferative sarcoma virus (MPSV) long terminal repeat (LTR) promoter.
(J:331604)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:331604 Leisegang M, et al., Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation. Clin Cancer Res. 2016 Jun 1;22(11):2734-43 |
All: |
1 reference(s) |
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