S100a16^em1.1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: S100a16^em1.1Gpt
• Name: S100 calcium binding protein A16; endonuclease-mediated mutation 1.1, GemPharmatech Co., Ltd
• MGI ID: MGI:7398436
• Gene: S100a16 Location: Chr3:90444561-90450458 bp, + strand Genetic Position: Chr3, 39.25 cM, cytoband F1-F2
• Alliance: S100a16^em1.1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• CRISPR-targeting floxed exons 2 and 3. Cre-mediated recombination removed exons 2 and 3. (J:330793)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any S100a16 Mutation: 15 strains or lines available

References

• Original: J:330793 Zhang WS, et al., S100a16 deficiency prevents hepatic stellate cells activation and liver fibrosis via inhibiting CXCR4 expression. Metabolism. 2022 Jul 29;135:155271
• All: 3 reference(s)