Blvra^tm1.1Rsto
Targeted Allele Detail

Summary

• Symbol: Blvra^tm1.1Rsto
• Name: biliverdin reductase A; targeted mutation 1.1, Roland Stocker
• MGI ID: MGI:7398535
• Gene: Blvra Location: Chr2:126912585-126939004 bp, + strand Genetic Position: Chr2, 61.76 cM, cytoband F3
• Alliance: Blvra^tm1.1Rsto page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:331733
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The targeting construct replaced exon 3 with an FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:331733)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Blvra Mutation: 34 strains or lines available

References

• Original: J:331733 Chen W, et al., Absence of the biliverdin reductase-a gene is associated with increased endogenous oxidative stress. Free Radic Biol Med. 2018 Feb 1;115:156-165
• All: 2 reference(s)