Lonp1^tm1.1Zzy
Targeted Allele Detail

Summary

• Symbol: Lonp1^tm1.1Zzy
• Name: lon peptidase 1, mitochondrial; targeted mutation 1.1, Zhongzhou Yang
• MGI ID: MGI:7398569
• Gene: Lonp1 Location: Chr17:56921297-56933887 bp, - strand Genetic Position: Chr17, 29.42 cM, cytoband D
• Alliance: Lonp1^tm1.1Zzy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:330310
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT-flanked neo cassette and loxP site were inserted upstream of exon 2 and a second loxP site was inserted downstream of exon 2 via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:330310)

Expression

In Mice Carrying this Mutation:

173 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lonp1 Mutation: 40 strains or lines available

References

• Original: J:330310 Lu B, et al., LonP1 orchestrates UPR^mt UPR^ER and mitochondrial dynamics to regulate heart function. bioRxiv. 2019 Mar
• All: 5 reference(s)