Hpcal1^em1Ylzg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hpcal1^em1Ylzg
• Name: hippocalcin-like 1; endonuclease-mediated mutation 1, Yonglong Zhang
• MGI ID: MGI:7407147
• Gene: Hpcal1 Location: Chr12:17740857-17841934 bp, + strand Genetic Position: Chr12, 8.13 cM
• Alliance: Hpcal1^em1Ylzg page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 and 3. (J:331711)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hpcal1 Mutation: 104 strains or lines available

References

• Original: J:331711 Chen T, et al., Hippocalcin-Like 1 blunts liver lipid metabolism to suppress tumorigenesis via directly targeting RUVBL1-mTOR signaling. Theranostics. 2022;12(17):7450-7464
• All: 1 reference(s)