Rr327^em1Mgn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr327^em1Mgn
• Name: regulatory region; endonuclease-mediated mutation 1, Mark A Magnuson
• MGI ID: MGI:7407248
• Synonyms: G6pc2^deltaEnhI
• Gene: Rr327 Location: unknown Genetic Position: Chr2, Syntenic
• Alliance: Rr327^em1Mgn page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intragenic deletion
• Rr327^em1Mgn involves 1 genes/genome features (Gm13613) View all
• CRISPR-targeting removed the G6pc2 enhancer sequence in an intron of Abcb11. (J:340414)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr327 Mutation: 1 strain or line available

References

• Original: J:340414 Keller MP, et al., An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets. Diabetes. 2023;:db230215
• All: 1 reference(s)