Adgrl4^tm1Adbg
Targeted Allele Detail

Summary

• Symbol: Adgrl4^tm1Adbg
• Name: adhesion G protein-coupled receptor L4; targeted mutation 1, Anna Dimberg
• MGI ID: MGI:7407284
• Gene: Adgrl4 Location: Chr3:151143519-151250718 bp, + strand Genetic Position: Chr3, 76.76 cM, cytoband H3-H4
• Alliance: Adgrl4^tm1Adbg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:330927
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced exons 3 through 13 with a transmembrane bounded lacZ reporter gene and a floxed neomycin resistance cassette. (J:330927)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adgrl4 Mutation: 58 strains or lines available

References

• Original: J:330927 Huang H, et al., ELTD1 deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma. Neuro Oncol. 2022 Mar 12;24(3):398-411
• All: 1 reference(s)